标题： 通过基底连接耦合的模型纤毛同步状态转换 显示英文标题

标题： Transitions in synchronization states of model cilia through basal-connection coupling

摘要： 尽管有证据表明不同真核细胞之间的鞭毛同步具有流体力学起源，但最近的实验显示，在单个多个鞭毛生物中，协调性则取决于基体的直接连接。 然而，这些连接如何导致协调目前尚不清楚。 在此，我们专注于模型双鞭毛生物{\it 布氏隐杆藻}，并提出一个最小模型，以说明其两个鞭毛由于流体力学和直接机械耦合而产生的同步现象。 根据细胞内耦合刚度的小幅变化，可以选择多种类型的协调。 这些包括延长的同相和反相同步，以及由系统自发对称性破缺引起的多种多稳态。 将同步性与细胞内刚度联系起来，可能会使鞭毛动力学成为探测细胞机械状态的一种工具。 显示英文摘要

摘要： Despite evidence for a hydrodynamic origin of flagellar synchronization between different eukaryotic cells, recent experiments have shown that in single multi-flagellated organisms, coordination hinges instead on direct basal body connections. The mechanism by which these connections leads to coordination, however, is currently not understood. Here we focus on the model biflagellate {\it Chlamydomonas reinhardtii}, and propose a minimal model for the synchronization of its two flagella as a result of both hydrodynamic and direct mechanical coupling. A spectrum of different types of coordination can be selected, depending on small changes in the stiffness of intracellular couplings. These include prolonged in-phase and anti-phase synchronization, as well as a range of multistable states induced by spontaneous symmetry breaking of the system. Linking synchrony to intracellular stiffness could lead to the use of flagellar dynamics as a probe for the mechanical state of the cell.